منابع مشابه
Stress Alters Rates and Types of Loss of Heterozygosity in Candida albicans
UNLABELLED Genetic diversity is often generated during adaptation to stress, and in eukaryotes some of this diversity is thought to arise via recombination and reassortment of alleles during meiosis. Candida albicans, the most prevalent pathogen of humans, has no known meiotic cycle, and yet it is a heterozygous diploid that undergoes mitotic recombination during somatic growth. It has been sho...
متن کاملCandida albicans
The secreted aspartyl proteinases of Candida albicans (products of the SAP genes) are thought to contribute to virulence through their effects on Candida adherence, invasion, and pathogenicity. From a single strain of C. albicans (WO-1) which expresses a phenotypic switching system, three secreted aspartyl proteinases have been identified as determined by molecular weight and N-terminal sequenc...
متن کاملCandida albicans
Figure 1. Fluorescent protein fusions in Candida albicans. Useful fluorescent markers for tracking subcellular structures in C. albicans include: DAPI (DNA); Nop1-GFP (green fluorescent protein, localizing to the nucleolus); Hhf1-GFP (chromatin); Tub2-GFP (microtubules, green); and Tub4-mCherry fluorescent protein (spindle pole bodies, red). Micrographs courtesy of Shelly Applen and Benjamin Ha...
متن کامل[Candida albicans].
Candida albicans is an opportunistic pathogen. Its proliferation in human hosts is believed to be controlled by immunologic mechanisms. The plasma membrane of the fungus posseses an H+-ATPase (PM-ATPase) which actively extrudes protons to generate an electrochemical gradient which is used in co-transport of nutrients. This ATPase is associated with the growth, dimorphism and pathogenicity of th...
متن کاملMorphogenesis in Candida albicans.
Candida albicans is termed a dimorphic fungus because it proliferates in either a yeast form or a hyphal form. The switch between these forms is the result of a complex interplay of external and internal factors and is coordinated in part by polarity-regulating proteins that are conserved among eukaryotic cells. However, yeast and hyphal cells are not the only morphological states of C. albican...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1981
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.145.2.896-903.1981